Asthma Trial: Patients with severe, uncontrolled asthma (treatment period of 24 weeks)

a. Subjects 18-75 years of age with severe asthma requiring medium to high-dose inhaled corticosteroids plus a second asthma controller in the previous 12 months b. Two or more asthma exacerbations in the previous 12 months requiring treatment with systemic corticosteroids c. Pre-screening FEV1 <80% of predicted d. Current smokers and ex-smokers with >10 pack-year […]

Asthma Trial: Patients with severe, uncontrolled asthma (treatment period of 52 weeks)

a. Subjects ≥12 years of age with severe asthma requiring medium to high-dose inhaled corticosteroids plus a second or third asthma controller b. Two or more asthma exacerbations in the previous 12 months requiring treatment with systemic corticosteroids c. FEV1 of ≥40% and ≤80% (≤90% for patients aged 12-18 years) d. Current smokers and ex-smokers […]