Dec 04, 2017 by Corporate


  • Male/Female 18-80 years of age
  • Sporadic or familial ALS
  • Less than or equal to 18 months since ALS symptom onset.
  • Slow Vital Capacity >60% of predicted value for gender/height/age at screening


  • Presence of tracheostomy
  • Exposure to PB/ TUDCA, or UDCA within 3 months prior to the Screening visit